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Forskolin is a weight loss and bodybuilding herb supplement, which has gained some attention in the market. It is alternatively marketed as Colforsin and Coleonol as well. It is an organic compound derived from the tuberous roots of Indian Coleus plant. It seems to have gained some visibility after it was featured by Dr Oz in one of his shows.

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Forskolin Weight Loss Supplements

Indian Coleus plant has been used for medicinal purposes for centuries. As part of Ayurvedic medicine(Ancient Indian medicine) tradition it was used for treating various heart conditions including high blood pressure, chest pain(angina), painful urination, convulsions and respiratory disorders such as asthma.

To get back to the point, there was only one peer reviewed scientific study done about Forskolin which was published in scientific journal. This study showed significant effects on overweight and obese men. It reduced body fat percentage and body fat mass. It also increased lean bone mass and serum testosterone levels in overweight and obese men. One should take notice that study was conducted only on men! Just one scientific study is definitely not sufficient enough to establish credibility of a supplement product.

Forskolin Weight Loss Supplements

activates enzyme adenylyl cyclase. This enzyme is involved in transmitting chemicals signals from outside of a cell, through cell membrane to the inside of a cell. Subsequent effect is increased level of chemical messenger called cyclic AMP(Adenosine monophosphate) or cAMP in short. cAMP is an important messenger in many biological processes. It is responsible for transferring effects of hormones like adrenaline, which can not pass through the cell membranes, to inside of the cell. Subsequently it plays role in regulation of glycogen, sugar and lipid metabolism. It is believed, because of this activation mechanism, it might be playing role in decreasing body fat and increasing lean bone mass.

Although fat reduction and lean bone mass increasing effects have not been studied that extensively, one of the well observed effect of Forskolin Weight Loss Supplements

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is that as a vasodilator and bronchodilator. It has been consistently observed to reduce blood pressure. It has been observed to be effective at reducing asthma attacks. Given this, one has to be careful, when using it as a weight loss supplement, because of you are taking blood pressure reducing medicines like calcium channel blockers or beta blockers, Forskolin Weight Loss Pills In 

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will work in conjunction with those medicine and there will be additive effect of reduction in blood pressure and it could turn out to be a serious issues. Just as high blood pressure is not good, a significantly low blood pressure is not good either.

In lab studies in test-tubes an on animals it has been observed that Forskolin Supplements

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interacts with melanin under skin and resulting effect is that of tanning! Don’t be surprised if it is claimed that the same miracle drug will loose weight, help build body and will do tanning at the same time without going to the sun!!

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Resveratrol is currently one of the most popular vitamins of this decade. It is a natural antioxidant found in red wines and grapes. The vitamin has many benefits such as helping in weight loss and preventing cancer. It is also a great anti-aging ingredient that can improve longevity and make you look younger. Resveratrol's anti-aging properties are one of the main reasons why Resveratrol became so popular. Resveratrol supplements were so popular that they were even featured on various TV shows such as "Barbara Walters", "60 Minutes", and others. However, there are side effects that you must know before you take this vitamin. These vary for each person. Resveratrol side effects depend on the person's composition and physical structure. Negative side effects are often caused by an overdose or underdose of Resveratrol. Therefore, if you want to avoid this, then you must make sure that you are taking the correct amount.

Most Common Resveratrol Symptoms

Negative effects are usually caused by an overdose and under dose. Resveratrol overdose can cause pain in your tendon, resulting in Tendinitis Pain. Improper dosage of the supplements can also cause acne breakouts, flu, colored urine, stomach pain, diarrhea, insomnia, and joint ache of the hands, hips, and feet. Resveratrol can also act as a blood thinner. If you are taking medication for blood thinning, consult your doctor before taking Resveratrol.

How to Prevent Negative Effects of Resveratrol

To prevent the possible negative effects, you must make sure that you are taking the proper dosage of Resveratrol. The proper resveratrol dosage can be between 50 mg to 250 mg per day. If you take the proper dosage of the vitamin, then you won't experience any problems. Consulting your physician before consuming Resveratrol can also help prevent you from having a negative reaction. Your physician can tell you more about your body's current situation and body structure. He will be able to tell you what sort of symptoms you can expect and guide you on the proper amount of Resveratrol you should consume.

Most of the side effects of Resveratrol can be easily avoided as long as you take Resveratrol properly. You should also do some research on the various Resveratrol supplements. Choose the Resveratrol supplement that has the fewest complaints about side effects by consumers. As long as you are careful in taking Resveratrol, you can enjoy its benefits without experiencing any of its side effects.

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Multiple Sclerosis and Resveratrol

If you just recently found out about Resveratrol, you may not understand all the scientific terms that people are talking about that are related to it. One of them is SIRT1, an enzyme that helps you deal with stress on a cellular level and also is involved in survival.

When the SIRT1 enzyme is activated, then you have the potential to live longer. Resveratrol is an SIRT1 enzyme activator.

One of the problems that many multiple sclerosis patients develop is optic neuritis. This is an inflammation of the optic nerve that causes permanent blindness. Some of the other problems seen in multiple sclerosis include paralysis, inability to write, muscle weakness, hearing loss, bladder problems, constipation, dizziness, and infections.

Researchers at the Department of Ophthalmology at the University of Pennsylvania Scheie Eye Institute in Philadelphia reported in the Investigations in Ophthalmology Vision Science journal in August 2007 that activating the SIRT1 enzyme protected the brain from optic neuritis in animals.

They induced multiple sclerosis in mice with an immunization. Fourteen days after immunization, there was significant retinal cell damage and inflammation set in.

Injecting the SIRT1 activators on the day of the immunization, 3 days later, 7 days later and 11 days later made a significant difference in the number of retinal cells that were damaged. One single dose of the SIRT1 activator was enough to preserve the eye cells and prevent the damage.

The researchers concluded that SIRT1 activators provide an important potential therapy to prevent nerve damage that leads to permanent blindness in those with multiple sclerosis and optic neuritis. They believed that SIRT1 activators combined with current immunotherapies to boost the immune system could be very important in the future.

Although this research doesn't come right out and say that Resveratrol helped the mice, we have the preliminary pieces of the puzzle in place. Resveratrol is an SIRT1 activator. SIRT1 activators reversed and prevented the damage usually seen in optic neuritis.