Forskolin is a weight loss and bodybuilding herb supplement, which has gained some attention in the market. It is alternatively marketed as Colforsin and Coleonol as well. It is an organic compound derived from the tuberous roots of Indian Coleus plant. It seems to have gained some visibility after it was featured by Dr Oz in one of his shows.

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Indian Coleus plant has been used for medicinal purposes for centuries. As part of Ayurvedic medicine(Ancient Indian medicine) tradition it was used for treating various heart conditions including high blood pressure, chest pain(angina), painful urination, convulsions and respiratory disorders such as asthma.

To get back to the point, there was only one peer reviewed scientific study done about Forskolin which was published in scientific journal. This study showed significant effects on overweight and obese men. It reduced body fat percentage and body fat mass. It also increased lean bone mass and serum testosterone levels in overweight and obese men. One should take notice that study was conducted only on men! Just one scientific study is definitely not sufficient enough to establish credibility of a supplement product.

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activates enzyme adenylyl cyclase. This enzyme is involved in transmitting chemicals signals from outside of a cell, through cell membrane to the inside of a cell. Subsequent effect is increased level of chemical messenger called cyclic AMP(Adenosine monophosphate) or cAMP in short. cAMP is an important messenger in many biological processes. It is responsible for transferring effects of hormones like adrenaline, which can not pass through the cell membranes, to inside of the cell. Subsequently it plays role in regulation of glycogen, sugar and lipid metabolism. It is believed, because of this activation mechanism, it might be playing role in decreasing body fat and increasing lean bone mass.

Although fat reduction and lean bone mass increasing effects have not been studied that extensively, one of the well observed effect of Forskolin Weight Loss Supplements

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is that as a vasodilator and bronchodilator. It has been consistently observed to reduce blood pressure. It has been observed to be effective at reducing asthma attacks. Given this, one has to be careful, when using it as a weight loss supplement, because of you are taking blood pressure reducing medicines like calcium channel blockers or beta blockers, Forskolin Weight Loss Pills In 

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will work in conjunction with those medicine and there will be additive effect of reduction in blood pressure and it could turn out to be a serious issues. Just as high blood pressure is not good, a significantly low blood pressure is not good either.

In lab studies in test-tubes an on animals it has been observed that Forskolin Supplements

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interacts with melanin under skin and resulting effect is that of tanning! Don’t be surprised if it is claimed that the same miracle drug will loose weight, help build body and will do tanning at the same time without going to the sun!!

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If you just recently found out about Resveratrol, you may not understand all the scientific terms that people are talking about that are related to it. One of them is SIRT1, an enzyme that helps you deal with stress on a cellular level and also is involved in survival.

When the SIRT1 enzyme is activated, then you have the potential to live longer. Resveratrol is an SIRT1 enzyme activator.

One of the problems that many multiple sclerosis patients develop is optic neuritis. This is an inflammation of the optic nerve that causes permanent blindness. Some of the other problems seen in multiple sclerosis include paralysis, inability to write, muscle weakness, hearing loss, bladder problems, constipation, dizziness, and infections.

Researchers at the Department of Ophthalmology at the University of Pennsylvania Scheie Eye Institute in Philadelphia reported in the Investigations in Ophthalmology Vision Science journal in August 2007 that activating the SIRT1 enzyme protected the brain from optic neuritis in animals.

They induced multiple sclerosis in mice with an immunization. Fourteen days after immunization, there was significant retinal cell damage and inflammation set in.

Injecting the SIRT1 activators on the day of the immunization, 3 days later, 7 days later and 11 days later made a significant difference in the number of retinal cells that were damaged. One single dose of the SIRT1 activator was enough to preserve the eye cells and prevent the damage.

The researchers concluded that SIRT1 activators provide an important potential therapy to prevent nerve damage that leads to permanent blindness in those with multiple sclerosis and optic neuritis. They believed that SIRT1 activators combined with current immunotherapies to boost the immune system could be very important in the future.

Although this research doesn't come right out and say that Resveratrol helped the mice, we have the preliminary pieces of the puzzle in place. Resveratrol is an SIRT1 activator. SIRT1 activators reversed and prevented the damage usually seen in optic neuritis.

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DHA and EPA fish oil have numerous benefits for the health. It is no secret that omega-3 essential fatty acids like DHA and EPA are needed by the body but do you know what exactly is the right DHA and EPA fish oil ratio that will give you all the benefits of omega-3? Before we talk about the correct DHA and EPA fish oil ratio, let us first take a look at DHA and EPA.

What is DHA?

DHA or docosahexaenoic acid is one kind of omega-3 essential fatty acid. It is an essential component of the tissues in the human brain and in the retina of the eyes. It plays an important role in proper nerve impulse transmission and in the overall functioning of the nervous system.

What is EPA?

EPA or eicosapentaenoic acid is the second type of omega-3 essential fatty acid. EPA is needed for the production of prostaglandins, which play a role in blood clotting and other functions of the arteries. It is also said to lower triglyceride levels, which greatly reduce the risk for the development of cardiovascular diseases.

Which essential fatty acid is more important: DHA or EPA?

While both are essential for one's health, DHA is generally considered to be more important than EPA. DHA is composed of 22 carbon bonds while EPA is composed of 20 carbon bonds, This makes it easy for DHA to be converted into EPA by losing two of its carbon bonds, but never the other way around.

What is the right DHA and EPA fish oil ratio?

Usually, most supplements contain a 18/12 fish oil ratio, that is, there is 18% DHA and 12% EPA in one gram of omega-3 capsule. This gives you 180 mg of DHA and 120 mg of EPA in one 1,000 mg capsule of fish oil.

However, there are some supplements that do contain much more DHA, approximately 250 mg, due to the importance of this essential fatty acid in our body which is often overlooked by a lot of people.

Of course, knowing the right DHA and EPA ratio is not the only important thing to consider in choosing a fish oil supplement. There are other factors to consider like purity, freshness, and kind of fish used. These elements are also important to consider to ensure that you get all the benefits of omega-3 fatty acids without the side effects.